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  • PIDD1抗原（重組蛋白）

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    • 品牌 : 通蔚生物
    • 目錄號(hào) : TW18097
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫(kù)存：40
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中文名稱(chēng)：  PIDD1抗原（重組蛋白）

英文名稱(chēng)： PIDD1 Antigen (Recombinant Protein)

別       名： p53-induced death domain protein 1; LRDD; PIDD

儲(chǔ)       存： 冷凍（-20℃）
相關(guān)類(lèi)別： 抗原

概述

Fusion protein corresponding to N terminal 146 amino acids of human PIDD1

技術(shù)規(guī)格

Full name:

p53-induced death domain protein 1

Synonyms:

LRDD; PIDD

Swissprot:

Q9HB75

Gene Accession:

BC014904

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The protein encoded by this gene contains a leucine-rich repeat and a death domain. This protein has been shown to interact with other death domain proteins, such as Fas (TNFRSF6)-associated via death domain (FADD) and MAP-kinase activating death domain-containing protein (MADD), and thus may function as an adaptor protein in cell death-related signaling processes. The expression of the mouse counterpart of this gene has been found to be positively regulated by the tumor suppressor p53 and to induce cell apoptosis in response to DNA damage, which suggests a role for this gene as an effector of p53-dependent apoptosis.