中文名稱: GYPC抗原(重組蛋白)
英文名稱: GYPC Antigen (Recombinant Protein)
別 名: GE; GPC; GPD; GYPD; CD236; PAS-2; CD236R; PAS-2
儲(chǔ) 存: 冷凍(-20℃)
相關(guān)類別: 抗原
概 述:
Fusion protein corresponding to N terminal 57 amino acids of human GYPC |
Full name: |
glycophorin C |
Synonyms: |
GE; GPC; GPD; GYPD; CD236; PAS-2; CD236R; PAS-2 |
Swissprot: |
P04921 |
Gene Accession: |
BC104246 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
Glycophorin C (GYPC) is an integral membrane glycoprotein. It is a minor species carried by human erythrocytes, but plays an important role in regulating the mechanical stability of red cells. A number of glycophorin C mutations have been described. The Gerbich and Yus phenotypes are due to deletion of exon 3 and 2, respectively. The Webb and Duch antigens, also known as glycophorin D, result from single point mutations of the glycophorin C gene. The glycophorin C protein has very little homology with glycophorins A and B. Alternate splicing results in multiple transcript variants. |