歡迎來到上海通蔚！

021-54845833/15800441009

品質(zhì)保證 · 通蔚試劑

當前位置: 首頁 > 科研產(chǎn)品 > 科研抗體 > 其他抗體 > CCN6 抗原（重組蛋白）

產(chǎn)品中心

  • CCN6 抗原（重組蛋白）

    規(guī)格：
    數(shù)量：

    購買數(shù)量

    價格：￥
    • 品牌 : 通蔚生物
    • 目錄號 : TW4114
    • 應用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫存：20
  • 商品詳情
  • 參考文獻
  • 說明書下載
  • 商品評論0
  • 相關產(chǎn)品

中文名稱： CCN6 抗原（重組蛋白）

英文名稱：CCN6 Antigen (Recombinant Protein)

儲     存： 冷凍（-20℃）

別     名： cellular communication network factor 6; PPD; LIBC; PPAC; WISP3; WISP-3

相關類別：抗原

概     述

Fusion protein corresponding to a region derived from 155-354 amino acids of human CCN6

技術(shù)規(guī)格

Full name:

cellular communication network factor 6

Synonyms:

PPD; LIBC; PPAC; WISP3; WISP-3

Swissprot:

O95389

Gene Accession:

BC105941

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a member of the WNT1 inducible signaling pathway (WISP) protein subfamily, which belongs to the connective tissue growth factor (CTGF) family. WNT1 is a member of a family of cysteine-rich, glycosylated signaling proteins that mediate diverse developmental processes. The CTGF family members are characterized by four conserved cysteine-rich domains: insulin-like growth factor-binding domain, von Willebrand factor type C module, thrombospondin domain and C-terminal cystine knot-like domain. This gene is overexpressed in colon tumors. It may be downstream in the WNT1 signaling pathway that is relevant to malignant transformation. Mutations of this gene are associated with progressive pseudorheumatoid dysplasia, an autosomal recessive skeletal disorder, indicating that the gene is essential for normal postnatal skeletal growth and cartilage homeostasis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]