歡迎來到上海通蔚!

021-54845833/15800441009

品質(zhì)保證 · 通蔚試劑

當(dāng)前位置: 首頁(yè) > 科研產(chǎn)品 > 科研抗體 > 其他抗體 > COPS5抗原(重組蛋白)

產(chǎn)品中心

  • COPS5抗原(重組蛋白)

    規(guī)格:
    數(shù)量:

    購(gòu)買數(shù)量

    價(jià)格:
    • 品牌 : 通蔚生物
    • 目錄號(hào) : TW16708
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫(kù)存:40
  • 商品詳情
  • 參考文獻(xiàn)
  • 說明書下載
  • 商品評(píng)論0
  • 相關(guān)產(chǎn)品

中文名稱: COPS5抗原(重組蛋白)

英文名稱: COPS5 Antigen (Recombinant Protein)

別      名: CSN5, JAB1, SGN5, MOV-34

儲(chǔ)       存: 冷凍(-20℃)

相關(guān)類別: 抗原

概述

Fusion protein corresponding to a region derived from 1-334 amino acids of human COPS5

技術(shù)規(guī)格

Full name:

COP9 constitutive photomorphogenic homolog subunit 5

Synonyms:

CSN5, JAB1, SGN5, MOV-34

Swissprot:

Q92905

Gene Accession:

BC001187

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein is reported to be involved in the degradation of cyclin-dependent kinase inhibitor CDKN1B/p27Kip1. It is also known to be an coactivator that increases the specificity of JUN/AP1 transcription factors