中文名稱: ST18 抗原(重組蛋白)
英文名稱: ST18 Antigen (Recombinant Protein)
別 名 : suppression of tumorigenicity 18, zinc finger; NZF3;
ZNF387; ZC2HC10
概 述
技術(shù)規(guī)格
Full name: |
suppression of tumorigenicity 18, zinc finger |
Synonyms: |
NZF3; ZNF387; ZC2HC10 |
Swissprot: |
O60284 |
Gene Accession: |
BC117147 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
ST18 (suppression of tumorigenicity 18), also known as ZNF387 ((zinc finger protein 387), is a 1,047 amino acid nuclear protein that is expressed at low levels in heart, liver, kidney, skeletal muscle, pancreas, testis, ovary and prostate. Containing six C2HC-type zinc fingers and an SMC domain, ST18 is a repressor protein that binds to DNA sequences containing a specific bipartite element. ST18 is considered a transcription factor that represses basal transcription activity from target promoters and Inhibits colony formation in cultured breast cancer cells. |