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  • ZC3H7A抗原（重組蛋白）

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    • 品牌 : 通蔚生物
    • 目錄號(hào) : TW6622
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫存：20
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中文名稱：ZC3H7A抗原（重組蛋白）

英文名稱： ZC3H7A Antigen (Recombinant Protein)

別     名： ZC3H7; HSPC055; ZC3HDC7

儲(chǔ)     存： 冷凍（-20℃）

相關(guān)類別：抗原

概     述

Fusion protein corresponding to a region derived from 805-971 amino acids of human ZC3H7A

技術(shù)規(guī)格

Full name:

zinc finger CCCH-type containing 7A

Synonyms:

ZC3H7; HSPC055; ZC3HDC7

Swissprot:

Q8IWR0

Gene Accession:

BC012575

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The zinc finger CCCH domain-containing protein 7A (ZC3H7A), also known as ZC3H7, HSPC055 or ZC3HDC7, is a 971 amino acid protein that contains a C3H1-type zinc finger domain, three C3H1-type zinc fingers and three TPR repeats. Belonging to the ZC3H12 family, ZC3H7A localizes to the nucleus. Existing as two alternatively spliced isoforms, ZC3H7A is encoded by a gene located on human chromosome 16p13.13. Chromosome 16 makes up nearly 3% of human cellular DNA and is associated with a variety of genetic disorders. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, though through the CREBBP gene which encodes a critical CREB binding protein. Signs of Rubinstein-Taybi include mental retardation and predisposition to tumor growth and white blood cell neoplasias. Crohn's disease is a gastrointestinal inflammatory condition associated with chromosome 16 through the NOD2 gene.