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  • CARD8抗原(重組蛋白)

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    • 品牌 : 通蔚生物
    • 目錄號(hào) : TW16869
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫(kù)存:90
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中文名稱(chēng):  CARD8抗原(重組蛋白)

英文名稱(chēng): CARD8 Antigen (Recombinant Protein)

別      名: NDPP; DACAR; DAKAR; NDPP1; TUCAN; CARDINAL

儲(chǔ)      存: 冷凍(-20℃)

相關(guān)類(lèi)別: 抗原

概  述:

Fusion protein corresponding to C terminal 250 amino acids of human CARD8


技術(shù)規(guī)格: 

Full name:

caspase recruitment domain family, member 8

Synonyms:

NDPP; DACAR; DAKAR; NDPP1; TUCAN; CARDINAL

Swissprot:

Q9Y2G2

Gene Accession:

BC056891

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The protein encoded by this gene belongs to the caspase recruitment domain (CARD)-containing family of proteins, which are involved in pathways leading to activation of caspases or nuclear factor kappa-B (NFKB). This protein may be a component of the inflammasome, a protein complex that plays a role in the activation of proinflammatory caspases. It is thought that this protein acts as an adaptor molecule that negatively regulates NFKB activation, CASP1-dependent IL1B secretion, and apoptosis. Polymorphisms in this gene may be associated with a susceptibility to rheumatoid arthritis.