中文名稱:FUNDC2抗原(重組蛋白)
英文名稱: FUNDC2 Antigen (Recombinant Protein)
別 名:DC44; HCC3; HCBP6; PD03104
儲 存: 冷凍(-20℃)
相關類別: 抗原
概 述:
Fusion protein corresponding to a region derived from 1-189 amino acids of human FUNDC2 |
Full name: |
FUN14 domain containing 2 |
Synonyms: |
DC44; HCC3; HCBP6; PD03104 |
Swissprot: |
Q9BWH2 |
Gene Accession: |
BC000255 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
FUNDC2 (FUN14 domain-containing protein 2), also known as HCC-3 (cervical cancer proto-oncogene 3 protein), HCBP6 (hepatitis C virus core-binding protein 6) or DC44, is a 189 amino acid protein belonging to the FUN14 family. The gene encoding FUNDC2 maps to human chromosome Xq28. The X and Y chromosomes are the human sex chromosomes. Chromosome X consists of about 153 million base pairs and nearly 1,000 genes. The combination of an X and Y chromosome lead to normal male development while two copies of X lead to normal female development. More than one copy of the X chromosome with a Y chromosome causes Klinefelter's syndrome. A single copy of X alone leads to Turner's syndrome. More than 2 copies of the X chromosome, in the absence of a Y chromosome, is known as Triple X syndrome. Color blindness, hemophilia, and Duchenne muscular dystrophy are well known X chromosome-linked conditions which affect males more frequently as males carry a single X chromosome. |