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  • EPS15L1抗原（重組蛋白）

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    • 品牌 : 通蔚生物
    • 目錄號 : TW17218
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
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中文名稱：EPS15L1抗原（重組蛋白）

英文名稱： EPS15L1 Antigen (Recombinant Protein)

別      名： EPS15R

儲      存： 冷凍（-20℃）

相關(guān)類別： 抗原

概  述：

Fusion protein corresponding to C terminal 250 amino acids of human EPS15L1


技術(shù)規(guī)格：

Full name:

epidermal growth factor receptor pathway substrate 15-like 1

Synonyms:

EPS15R

Swissprot:

Q9UBC2

Gene Accession:

BC131590

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

Epidermal growth factor receptor substrate 15-like 1 is a protein that in humans is encoded by the EPS15L1gene. Seems to be a constitutive component of clathrin-coated pits that is required for receptor-mediated endocytosis. Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin receptor (TFR); internalization of ITGB1 as DAB2-dependent cargo but not TFR seems to require association with DAB2. Interacts with EPS15, AGFG1/HRB and AGFG2/HRBL. Associates with the clathrin-associated adapter protein complex 2 (AP-2) By similarity. Interacts with FCHO1. Interacts with FCHO2. Interacts (via EH domains) with DAB2.