歡迎來到上海通蔚！

021-54845833/15800441009

品質(zhì)保證 · 通蔚試劑

當(dāng)前位置: 首頁 > 科研產(chǎn)品 > 科研抗體 > 其他抗體 > COA7抗原（重組蛋白）

產(chǎn)品中心

  • COA7抗原（重組蛋白）

    規(guī)格：
    數(shù)量：

    購(gòu)買數(shù)量

    價(jià)格：￥
    • 品牌 : 通蔚生物
    • 目錄號(hào) : TW16707
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫存：40
  • 商品詳情
  • 參考文獻(xiàn)
  • 說明書下載
  • 商品評(píng)論0
  • 相關(guān)產(chǎn)品

中文名稱： COA7抗原（重組蛋白）
英文名稱： COA7 Antigen (Recombinant Protein)
別      名： RESA1; SELRC1; C1orf163
儲(chǔ)      存： 冷凍（-20℃）
相關(guān)類別： 抗原

概述

Full length fusion protein

技術(shù)規(guī)格

Full name:

cytochrome c oxidase assembly factor 7 (putative)

Synonyms:

RESA1; SELRC1; C1orf163

Swissprot:

Q96BR5

Gene Accession:

BC015313

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The cytochrome c oxidase (COX) family of proteins function as the final electron donor in the respiratory chain to drive a proton gradient across the inner mitochondrial membrane, ultimately resulting in the production of water. COA7 (cytochrome c oxidase assembly factor 7), also known as RESA1, SELRC1 or C1orf163, is a 231 amino acid mitochondrial protein that belongs to the hcp beta-lactamase family. Consisting of five Sel1-like repeats, COA7 may be associated with respiratory chain assembly. COA7 is encoded by a gene located on human chromosome 1p32.3. Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene, which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration.