中文名稱: LDOC1 抗原(重組蛋白)
英文名稱: LDOC1 Antigen (Recombinant Protein)
別 名: leucine zipper, down-regulated in cancer 1; Mar7; BCUR1; Mart7
儲 存: 冷凍(-20℃)
相關(guān)類別: 抗原
概 述
Fusion protein corresponding to N terminal 132 amino acids of human LDOC1 |
Full name: |
leucine zipper, down-regulated in cancer 1 |
Synonyms: |
Mar7; BCUR1; Mart7 |
Swissprot: |
O95751 |
Gene Accession: |
BC003104 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
The protein encoded by this gene contains a leucine zipper-like motif and a proline-rich region that shares marked similarity with an SH3-binding domain. The protein localizes to the nucleus and is down-regulated in some cancer cell lines. It is thought to regulate the transcriptional response mediated by the nuclear factor kappa B (NF-kappaB). The gene has been proposed as a tumor suppressor gene whose protein product may have an important role in the development and/or progression of some cancers. |