Background: |
There are approximately 40 known eukaryotic LIM proteins, so named for the LIM domains they contain. LIM domains are highly conserved cysteine-rich structures containing 2 zinc fingers. Although zinc fingers usually function by binding to DNA or RNA, the LIM motif probably mediates protein-protein interactions. LIM kinase-1 and LIM kinase-2 belong to a small subfamily with a unique combination of 2 N-terminal LIM motifs and a C-terminal protein kinase domain. |
Applications: |
WB, IHC, IF |
Name of antibody: |
LIMK2 |
Immunogen: |
Synthesized peptide derived from internal of human LIMK2. |
Full name: |
LIM domain kinase 2 |
Synonyms: |
0 |
SwissProt: |
P53671 |
IHC positive control: |
Human heart tissue |
IHC Recommend dilution: |
50-100 |
WB Predicted band size: |
72 kDa |
WB Positive control: |
HepG2 cells and Huvec cells lysates |
WB Recommended dilution: |
500-3000 |
IF positive control: |
Hela cells |
IF Recommend dilution: |
100-500 |