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中文名稱：兔抗CBX5(Ab-92)多克隆抗體
英文名稱： Anti-CBX5(Ab-92) rabbit polyclonal antibody
別 名： HP1; HP1A; HEL25
抗 原： CBX5(Ab-92)
儲 存： 冷凍（-20℃） 避光
宿 主： Rabbit
相關類別： 一抗
反應種屬： Human
標 記 物： Unconjugate
克隆類型： Unconjugate
技術規(guī)格
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Background: |
Component of heterochromatin that recognizes and binds histone H3 tails methylated at 'Lys-9' (H3K9me), leading to epigenetic repression. In contrast, it is excluded from chromatin when 'Tyr-41' of histone H3 is phosphorylated (H3Y41ph). Can interact with lamin-B receptor (LBR). This interaction can contribute to the association of the heterochromatin with the inner nuclear membrane. Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins. |
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Applications: |
WB, IHC |
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Name of antibody: |
CBX5(Ab-92) |
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Immunogen: |
Synthesized non-phosphopeptide derived from human HP1 alpha around the phosphorylation site of serine 92 (R-K-S(p)-N-F). |
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Full name: |
chromobox homolog 5 |
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Synonyms： |
HP1; HP1A; HEL25 |
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SwissProt: |
P45973 |
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IHC positive control: |
Human braina tissue |
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IHC Recommend dilution: |
50-100 |
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WB Predicted band size: |
22 kDa |
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WB Positive control: |
Jurkat cells treated with insulin (0.01U/ml, 15mins) lysate |
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WB Recommended dilution: |
500-3000 |
