中文名稱: 兔抗MORF4L1多克隆抗體
英文名稱: Anti-MORF4L1 rabbit polyclonal antibody
別 名: Eaf3; MEAF3; MRG15; FWP006; S863-6; HsT17725; MORFRG15
相關(guān)類別: 一抗
抗 原: MORF4L1
儲 存: 冷凍(-20℃)
宿 主: Rabbit
反應(yīng)種屬: Human, Mouse, Rat
標 記 物: Unconjugate
克隆類型: rabbit polyclonal
技術(shù)規(guī)格
Background: |
The members of the mortality factor family include mortality factor 4 (MORF4), MORF4L1 (also known as MRG15) and MORF4-related gene X (MRGX). The human MORF4 gene maps to chromosome 4q33-q34.1. MORF4 induces a senescent-like phenotype in complementation group B immortal cell lines. The genes encoding MRG15 and MRGX map to chromosomes 15q24 and Xq22, respectively. MORF4, MORF4L1 and MRGX each contain a C-terminal leucine zipper. An association between MORF4L1, Rb (retinoblastoma tumor suppressor) and PAM14 (protein associated with MORF4L1) suggests a role for MORF4L1 in transcription regulation. MORF4L1 also associates with the histone acetyl transferase MOF. In addition, MORF4 and MRGX interact with mSin3A and TLE (transducin-like enhancer of split). The MORF/ mSin3A/TLE association may repress transcription. In Purkinje cells, MORF4L1 localizes to the dendrites and the nuclei. |
Applications: |
ELISA, IHC |
Name of antibody: |
MORF4L1 |
Immunogen: |
Synthetic peptide of human MORF4L1 |
Full name: |
mortality factor 4 like 1 |
Synonyms: |
Eaf3; MEAF3; MRG15; FWP006; S863-6; HsT17725; MORFRG15 |
SwissProt: |
Q9UBU8 |
ELISA Recommended dilution: |
5000-10000 |
IHC positive control: |
Human lung cancer and Human tonsil |
IHC Recommend dilution: |
30-150 |