中文名稱: ZBTB44 抗原(重組蛋白)
英文名稱: ZBTB44 Antigen (Recombinant Protein)
別 名: zinc finger and BTB domain containing 44; BTBD15; ZNF851; HSPC063
相關(guān)類別:抗原
儲 存: 冷凍(-20℃)
概 述
Full name: |
zinc finger and BTB domain containing 44 |
Synonyms: |
BTBD15; ZNF851; HSPC063 |
Swissprot: |
Q8NCP5 |
Gene Accession: |
BC030580 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. Zinc finger and BTB domain-containing protein 44 (ZBTB44), also known as BTBD15, is a 570 amino acid member of the Krüppel C2H2-type zinc-finger protein family. Localized to the nucleus, ZBTB44 contains a BTB domain, also known as a POZ domain, which inhibits DNA binding and mediates homotypic and heterotypic dimerization. Characteristics of the BTB domain suggest that ZBTB44 functions as a transcription regulator. Four isoforms of ZBTB44 have been identified. |