中文名稱:TBP 抗原(重組蛋白)
英文名稱:TBP Antigen (Recombinant Protein)
相關(guān)類別:抗原
儲 存: 冷凍(-20℃)
概 述
技術(shù)規(guī)格
Background: |
This gene encodes TBP, the TATA-binding protein. A distinctive feature of TBP is a long string of glutamines in the N-terminus. This region of the protein modulates the DNA binding activity of the C terminus, and modulation of DNA binding affects the rate of transcription complex formation and initiation of transcription. The number of CAG repeats encoding the polyglutamine tract is usually 32-39, and expansion of the number of repeats increases the length of the polyglutamine string and is associated with spinocerebellar ataxia 17, a neurodegenerative disorder classified as a polyglutamine disease. |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Expression system: |
Escherichia coli |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Gene Accession: |
BC109054 |
Swissprot: |
P20226 |
Synonyms: |
HDL4; GTF2D; SCA17; TFIID; GTF2D1 |
Full name: |
TATA box binding protein |