中文名稱: SHPK 抗原(重組蛋白)
英文名稱: SHPK Antigen (Recombinant Protein)
別 名: sedoheptulokinase; SHK; CARKL
儲(chǔ) 存: 冷凍(-20℃)
相關(guān)類別:抗原
技術(shù)規(guī)格
Full name: |
sedoheptulokinase |
Synonyms: |
SHK; CARKL |
Swissprot: |
Q9UHJ6 |
Gene Accession: |
BC020543 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
The protein encoded by this gene has weak homology to several carbohydrate kinases, a class of proteins involved in the phosphorylation of sugars as they enter a cell, inhibiting return across the cell membrane. Sequence variation between this novel gene and known carbohydrate kinases suggests the possibility of a different substrate, cofactor or changes in kinetic properties distinguishing it from other carbohydrate kinases. The gene resides in a region commonly deleted in cystinosis patients, suggesting a role as a modifier for the cystinosis phenotype. The genomic region is also rich in Alu repetitive sequences, frequently involved in chromosomal rearrangements. |