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  • PCSK5 抗原（重組蛋白）

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    • 品牌 : 通蔚生物
    • 目錄號(hào) : TW18329
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫(kù)存：90
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中文名稱：PCSK5 抗原（重組蛋白）

英文名稱： PCSK5 Antigen (Recombinant Protein)

別      名： proprotein convertase subtilisin/kexin type 5; PC5; PC6; PC6A; SPC6

儲(chǔ)      存： 冷凍（-20℃）

相關(guān)類別： 抗原

概      述：

Fusion protein corresponding to a region derived from 115-314 amino acids of human PCSK5


技術(shù)規(guī)格：

Full name:

proprotein convertase subtilisin/kexin type 5

Synonyms:

PC5; PC6; PC6A; SPC6

Swissprot:

Q92824

Gene Accession:

BC012064

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an initial autocatalytic processing event in the ER to generate a heterodimer which exits the ER. It then sorts to the trans-Golgi network where a second autocatalytic event takes place and the catalytic activity is acquired. This encoded protein is widely expressed and one of the seven basic amino acid-specific members which cleave their substrates at single or paired basic residues. It mediates posttranslational endoproteolytic processing for several integrin alpha subunits and is thought to process prorenin, pro-membrane type-1 matrix metalloproteinase and HIV-1 glycoprotein gp160. Alternative splicing results in multiple transcript variants, some of which encode distinct isoforms, including a protease packaged into dense core granules (PC5A) and a type 1 membrane bound protease (PC5B).