中文名稱: CD46 抗原(重組蛋白)
概 述
技術(shù)規(guī)格
Full name: |
CD46 molecule, complement regulatory protein |
Synonyms: |
MCP; TLX; AHUS2; MIC10; TRA2.10 |
Swissprot: |
P15529 |
Gene Accession: |
BC030594 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. |