購(gòu)物車
幫助
021-54845833/15800441009
中文名稱： 兔抗PDZD3多克隆抗體
英文名稱： Anti-PDZD3 rabbit polyclonal antibody
別 名： PDZ domain containing 3; IKEPP; PDZK2; NHERF4
相關(guān)類別： 一抗
儲(chǔ) 存： 冷凍（-20℃）
宿 主： Rabbit
抗 原： PDZD3
反應(yīng)種屬： Human
標(biāo) 記 物： Unconjugate
克隆類型： rabbit polyclonal
技術(shù)規(guī)格
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Background: |
Guanylyl cyclase C (GCC, or GUCY2C; MIM 601330) produces cGMP following the binding of either endogenous ligands or heat-stable enterotoxins secreted by E. coli and other enteric bacteria. Activation of GCC initiates a signaling cascade that leads to phosphorylation of the cystic fibrosis transmembrane conductance regulator (CFTR; MIM 602421), followed by a net efflux of ions and water into the intestinal lumen. IKEPP is a regulatory protein that associates with GCC and regulates the amount of cGMP produced following receptor stimulation (Scott et al., 2002 [PubMed 11950846]). |
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Applications: |
ELISA, IHC |
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Name of antibody: |
PDZD3 |
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Immunogen: |
Fusion protein of human PDZD3 |
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Full name: |
PDZ domain containing 3 |
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Synonyms: |
IKEPP; PDZK2; NHERF4 |
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SwissProt: |
Q86UT5 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human cervical cancer and Human tonsil |
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IHC Recommend dilution: |
25-100 |
