購(gòu)物車
幫助
021-54845833/15800441009
中文名稱： 兔抗PDIA3多克隆抗體
英文名稱： Anti-PDIA3 rabbit polyclonal antibody
別 名： PDIA3; ER60; ERp57; ERp60; ERp61; GRP57; GRP58; HsT17083; P58; PI-PLC
相關(guān)類別： 一抗
儲(chǔ) 存： 冷凍（-20℃） 避光
宿 主： Rabbit
抗 原： PDIA3
反應(yīng)種屬： Human, Mouse, Rat
標(biāo) 記 物： Unconjugate
克隆類型： rabbit polyclonal
技術(shù)規(guī)格
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Background: |
Secretory proteins translocate into the endoplasmic reticulum (ER) after their synthesis where they are post-translationally modified and properly folded. To reach their native conformation, many secretory proteins require the formation of intra- or inter-molecular disulfide bonds. This process is called oxidative protein folding. Disulfide isomerase (PDI) has two thioredoxin homology domains and catalyzes the formation and isomerization of these disulfide bonds. Other ER resident proteins that possess the thioredoxin homology domains, including endoplasmic reticulum stress protein 57 (ERp57), constitute the PDI family. ERp57 interacts with calnexin and calreticulin and is suggested to play a role in the isomerization of disulfide bonds on certain glycoproteins. |
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Applications: |
WB |
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Name of antibody: |
PDIA3 |
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Immunogen: |
Fusion protein of human PDIA3 |
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Full name: |
protein disulfide isomerase family A, member 3 |
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Synonyms： |
PDIA3; ER60; ERp57; ERp60; ERp61; GRP57; GRP58; HsT17083; P58; PI-PLC |
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SwissProt: |
P30101 |
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WB Predicted band size: |
57 kDa |
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WB Positive control: |
HT-29, PC-3, HepG2, NIH3T3, U2OS, HeLa, Jurkat and Raw264.7 cells |
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WB Recommended dilution: |
500-2000 |
