技術(shù)規(guī)格
Background:
The protein encoded by this gene is a cytokine receptor that specifically mediates the biological effects of interleukin 9 (IL9). The functional IL9 receptor complex requires this protein as well as the interleukin 2 receptor, gamma (IL2RG), a common gamma subunit shared by the receptors of many different cytokines. The ligand binding of this receptor leads to the activation of various JAK kinases and STAT proteins, which connect to different biologic responses. This gene is located at the pseudoautosomal regions of X and Y chromosomes. Genetic studies suggested an association of this gene with the development of asthma. Multiple pseudogenes on chromosome 9, 10, 16, and 18 have been described. Alternatively spliced transcript variants have been found for this gene.
Applications:
ELISA, WB, IHC
Name of antibody:
IL9R
Immunogen:
Synthetic peptide of human IL9R
Full name:
interleukin 9 receptor
Synonyms:
CD129; IL-9R
SwissProt:
Q01113
ELISA Recommended dilution:
5000-10000
IHC positive control:
Human brain
IHC Recommend dilution:
25-100
WB Predicted band size:
57 kDa
WB Positive control:
Jurkat,RAW264.7,HUVEC and A549 cell lysates
WB Recommended dilution:
200-1000