中文名稱:GGA2 抗原(重組蛋白)
英文名稱: GGA2 Antigen (Recombinant Protein)
別 名: golgi associated, gamma adaptin ear containing, ARF binding protein 2; VEAR
儲(chǔ) 存: 冷凍(-20℃)
相關(guān)類別: 抗原
概 述:
Fusion protein corresponding to a region derived from 414-613 amino acids of human GGA2 |
Full name: |
golgi associated, gamma adaptin ear containing, ARF binding protein 2 |
Synonyms: |
VEAR |
Swissprot: |
Q9UJY4 |
Gene Accession: |
BC000284 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
This gene encodes a member of the Golgi-localized, gamma adaptin ear-containing, ARF-binding (GGA) family. This family includes ubiquitous coat proteins that regulate the trafficking of proteins between the trans-Golgi network and the lysosome. These proteins share an amino-terminal VHS domain which mediates sorting of the mannose 6-phosphate receptors at the trans-Golgi network. They also contain a carboxy-terminal region with homology to the ear domain of gamma-adaptins. This family member may play a significant role in cargo molecules regulation and clathrin-coated vesicle assembly. |