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  • KLF17抗原(重組蛋白)

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    • 品牌 : 通蔚生物
    • 目錄號(hào) : TW17474
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫(kù)存:90
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中文名稱:KLF17抗原(重組蛋白)

英文名稱: KLF17 Antigen (Recombinant Protein)

別       名:ZNF393; Zfp393; RP4-675G8.1

儲(chǔ)       存: 冷凍(-20℃)

相關(guān)類別: 抗原

概  述:

Fusion protein corresponding to C terminal 250 amino acids of human KLF17


技術(shù)規(guī)格

Full name:

Kruppel-like factor 17

Synonyms:

ZNF393; Zfp393; RP4-675G8.1

Swissprot:

Q5JT82

Gene Accession:

BC049844

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

Krueppel-like factor 17 is a protein that in humans is encoded by the KLF17 gene. Transcription repressor that binds to the promoter of target genes and prevents their expression. Acts as a negative regulator of epithelial-mesenchymal transition and metastasis in breast cancer. Specifically binds the 5'-CACCC-3' sequence in the promoter of ID1, a key metastasis regulator in breast cancer, and repress its expression. May be a germ cell-specific transcription factor that plays important roles in spermatid differentiation and oocyte development.