中文名稱:KLF17抗原(重組蛋白)
英文名稱: KLF17 Antigen (Recombinant Protein)
別 名:ZNF393; Zfp393; RP4-675G8.1
儲(chǔ) 存: 冷凍(-20℃)
相關(guān)類別: 抗原
概 述:
Fusion protein corresponding to C terminal 250 amino acids of human KLF17 |
Full name: |
Kruppel-like factor 17 |
Synonyms: |
ZNF393; Zfp393; RP4-675G8.1 |
Swissprot: |
Q5JT82 |
Gene Accession: |
BC049844 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
Krueppel-like factor 17 is a protein that in humans is encoded by the KLF17 gene. Transcription repressor that binds to the promoter of target genes and prevents their expression. Acts as a negative regulator of epithelial-mesenchymal transition and metastasis in breast cancer. Specifically binds the 5'-CACCC-3' sequence in the promoter of ID1, a key metastasis regulator in breast cancer, and repress its expression. May be a germ cell-specific transcription factor that plays important roles in spermatid differentiation and oocyte development. |