中文名稱(chēng):ZFYVE27抗原(重組蛋白)
英文名稱(chēng): ZFYVE27 Antigen (Recombinant Protein)
別 名: SPG33; PROTRUDIN
儲(chǔ) 存: 冷凍(-20℃)
相關(guān)類(lèi)別: 抗原
概 述:
Fusion protein corresponding to a region derived from 212-411 amino acids of human ZFYVE27 |
Full name: |
zinc finger FYVE-type containing 27 |
Synonyms: |
SPG33; PROTRUDIN |
Swissprot: |
Q5T4F4 |
Gene Accession: |
BC030621 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
This gene encodes a protein with several transmembrane domains, a Rab11-binding domain and a lipid-binding FYVE finger domain. The encoded protein appears to promote neurite formation. A mutation in this gene has been reported to be associated with hereditary spastic paraplegia, however the pathogenicity of the mutation, which may simply represent a polymorphism, is unclear. |