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  • FH抗原(重組蛋白)

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    • 品牌 : 通蔚生物
    • 目錄號 : TW17301
    • 應用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現貨
    • 商品庫存:90
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中文名稱:  FH抗原(重組蛋白)

英文名稱 FH Antigen (Recombinant Protein)

別      名: MCL; LRCC; HLRCC; MCUL1

儲      存: 冷凍(-20℃)

相關類別: 抗原

概  述:

Fusion protein corresponding to C terminal 250 amino acids of human FH


技術規(guī)格:

Full name:

fumarate hydratase

Synonyms:

MCL; LRCC; HLRCC; MCUL1

Swissprot:

P07954

Gene Accession:

BC003108

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The protein encoded by this gene is an enzymatic component of the tricarboxylic acid (TCA) cycle, or Krebs cycle, and catalyzes the formation of L-malate from fumarate. It exists in both a cytosolic form and an N-terminal extended form, differing only in the translation start site used. The N-terminal extended form is targeted to the mitochondrion, where the removal of the extension generates the same form as in the cytoplasm. It is similar to some thermostable class II fumarases and functions as a homotetramer. Mutations in this gene can cause fumarase deficiency and lead to progressive encephalopathy.