中文名稱:RETREG1抗原(重組蛋白)
英文名稱: RETREG1 Antigen (Recombinant Protein)
別 名: JK1; JK-1; FAM134B
儲(chǔ) 存: 冷凍(-20℃)
相關(guān)類別: 抗原
概 述:
Fusion protein corresponding to a region derived from 357-497 amino acids of human RETREG1 |
Full name: |
reticulophagy regulator 1 |
Synonyms: |
JK1; JK-1; FAM134B |
Swissprot: |
Q9H6L5 |
Gene Accession: |
BC030517 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
The protein encoded by this gene is a cis-Golgi transmembrane protein that may be necessary for the long-term survival of nociceptive and autonomic ganglion neurons. Mutations in this gene are a cause of hereditary sensory and autonomic neuropathy type IIB (HSAN IIB), and this gene may also play a role in susceptibility to vascular dementia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |