中文名稱: PPIB抗原(重組蛋白)
英文名稱: PPIB Antigen (Recombinant Protein)
別 名: OI9; CYPB; SCYLP; CYP-S1
儲 存: 冷凍(-20℃)
相關(guān)類別: 抗原
概 述:
Fusion protein corresponding to a region derived from 34-216 amino acids of human PPIB |
Full name: |
peptidylprolyl isomerase B (cyclophilin B) |
Synonyms: |
OI9; CYPB; SCYLP; CYP-S1 |
Swissprot: |
P23284 |
Gene Accession: |
BC001125 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
The protein encoded by this gene is a cyclosporine-binding protein and is mainly located within the endoplasmic reticulum. It is associated with the secretory pathway and released in biological fluids. This protein can bind to cells derived from T- and B-lymphocytes, and may regulate cyclosporine A-mediated immunosuppression. Variants have been identified in this protein that give rise to recessive forms of osteogenesis imperfecta. |