中文名稱: PPP1R1B抗原(重組蛋白)
英文名稱: PPP1R1B Antigen (Recombinant Protein)
別 名: DARPP32; DARPP-32
相關(guān)類別: 抗原
概 述:
Fusion protein corresponding to a region derived from 37-204 amino acids of human PPP1R1B |
Full name: |
protein phosphatase 1, regulatory (inhibitor) subunit 1B |
Synonyms: |
DARPP32; DARPP-32 |
Swissprot: |
Q9UD71 |
Gene Accession: |
BC001519 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
This gene encodes a bifunctional signal transduction molecule. Dopaminergic and glutamatergic receptor stimulation regulates its phosphorylation and function as a kinase or phosphatase inhibitor. As a target for dopamine, this gene may serve as a therapeutic target for neurologic and psychiatric disorders. Multiple transcript variants encoding different isoforms have been found for this gene |