購物車
幫助
021-54845833/15800441009
中文名稱： RNF128 抗原（重組蛋白）
英文名稱： RNF128 Antigen (Recombinant Protein)
別 名： ring finger protein 128; GRAIL
儲 存： 冷凍（-20℃）
概 述
技術(shù)規(guī)格
|
Full name: |
ring finger protein 128 |
|
Synonyms: |
GRAIL |
|
Swissprot: |
Q8TEB7 |
|
Gene Accession: |
BC063404 |
|
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
|
Expression system: |
Escherichia coli |
|
Tags: |
His tag C-Terminus, GST tag N-Terminus |
|
Background: |
The protein encoded by this gene is a type I transmembrane protein that localizes to the endocytic pathway. This protein contains a RING zinc-finger motif and has been shown to possess E3 ubiquitin ligase activity. Expression of this gene in retrovirally transduced T cell hybridoma significantly inhibits activation-induced IL2 and IL4 cytokine production. Induced expression of this gene was observed in anergic CD4(+) T cells, which suggested a role in the induction of anergic phenotype. Alternatively spliced transcript variants encoding distinct isoforms have been reported. |
