中文名稱: EDA2R抗原(重組蛋白)
英文名稱: EDA2R Antigen (Recombinant Protein)
別 名: XEDAR; EDAA2R; EDA-A2R; TNFRSF27
儲(chǔ) 存: 冷凍(-20℃)
相關(guān)類別: 抗原
概 述:
Fusion protein corresponding to a region derived from C terminal 138 amino acids of human EDA2R |
Full name: |
ectodysplasin A2 receptor |
Synonyms: |
XEDAR; EDAA2R; EDA-A2R; TNFRSF27 |
Swissprot: |
Q9HAV5 |
Gene Accession: |
BC034919 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
EDA-A1 and EDA-A2 are two isoforms of ectodysplasin that are encoded by the anhidrotic ectodermal dysplasia (EDA) gene. Mutations in EDA give rise to a clinical syndrome characterized by loss of hair, sweat glands, and teeth. The protein encoded by this gene specifically binds to EDA-A2 isoform. This protein is a type III transmembrane protein of the TNFR (tumor necrosis factor receptor) superfamily, and contains 3 cysteine-rich repeats and a single transmembrane domain but lacks an N-terminal signal peptide. Alternatively spliced transcript variants have been found for this gene. |