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  • TNFRSF11B抗原（重組蛋白）

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    • 品牌 : 通蔚生物
    • 目錄號(hào) : TW17307
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫(kù)存：40
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中文名稱(chēng)： TNFRSF11B抗原（重組蛋白）

英文名稱(chēng)： TNFRSF11B Antigen (Recombinant Protein)

別       名： OPG, TR1, OCIF

儲(chǔ)       存： 冷凍（-20℃）

相關(guān)類(lèi)別： 抗原

概述

Fusion protein corresponding to a region derived from 195-365 amino acids of human TNFRSF11B

技術(shù)規(guī)格

Full name:

tumor necrosis factor receptor superfamily, member 11b

Synonyms:

OPG, TR1, OCIF

Swissprot:

O00300

Gene Accession:

BC030155

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined.