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  • RRM1抗原(重組蛋白)

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    • 品牌 : 通蔚生物
    • 目錄號(hào) : TW17154
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫(kù)存:40
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中文名稱: RRM1抗原(重組蛋白)

英文名稱: RRM1 Antigen (Recombinant Protein)

別       名: R1; RR1; RIR1

儲(chǔ)       存: 冷凍(-20℃)

相關(guān)類別: 抗原

概述

Fusion protein corresponding to C terminal 226 amino acids of human RRM1

技術(shù)規(guī)格

Full name:

Ribonucleotide reductase M1

Synonyms:

R1; RR1; RIR1

Swissprot:

P23921

Gene Accession:

BC006498

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes one of two non-identical subunits that constitute ribonucleoside-diphosphate reductase, an enzyme essential for the production of deoxyribonucleotides prior to DNA synthesis in S phase of dividing cells. It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region.