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  • COMP抗原(重組蛋白)

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    • 品牌 : 通蔚生物
    • 目錄號(hào) : TW16972
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫(kù)存:90
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中文名稱(chēng):  COMP抗原(重組蛋白)

英文名稱(chēng): COMP Antigen (Recombinant Protein)

別      名: MED; EDM1; EPD1; PSACH; THBS5

儲(chǔ)      存: 冷凍(-20℃)

相關(guān)類(lèi)別: 抗原

概  述:

Fusion protein corresponding to a region derived from C terminal 215 amino acids of human COMP


技術(shù)規(guī)格: 

Full name:

cartilage oligomeric matrix protein

Synonyms:

MED; EDM1; EPD1; PSACH; THBS5

Swissprot:

P49747

Gene Accession:

BC125092

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The protein encoded by this gene is a noncollagenous extracellular matrix (ECM) protein. It consists of five identical glycoprotein subunits, each with EGF-like and calcium-binding (thrombospondin-like) domains. Oligomerization results from formation of a five-stranded coiled coil and disulfides. Binding to other ECM proteins such as collagen appears to depend on divalent cations. Mutations can cause the osteochondrodysplasias pseudochondroplasia (PSACH) and multiple epiphyseal dysplasia (MED).