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  • PPP1R12A 抗原(重組蛋白)

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    • 品牌 : 通蔚生物
    • 目錄號(hào) : TW17534
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫(kù)存:75
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中文名稱:  PPP1R12A 抗原(重組蛋白

英文名稱: PPP1R12A Antigen (Recombinant Protein)

別      名: protein phosphatase 1, regulatory subunit 12A; MBS; M130; MYPT1

儲(chǔ)      存: 冷凍(-20℃)

相關(guān)類別: 抗原

概述

Fusion protein corresponding to a region derived from 682-864 amino acids of human PPP1R12A


技術(shù)規(guī)格

Full name:

protein phosphatase 1, regulatory subunit 12A

Synonyms:

MBS; M130; MYPT1

Swissprot:

O14974

Gene Accession:

BC111752

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

Myosin phosphatase target subunit 1, which is also called the myosin-binding subunit of myosin phosphatase, is one of the subunits of myosin phosphatase. Myosin phosphatase regulates the interaction of actin and myosin downstream of the guanosine triphosphatase Rho. The small guanosine triphosphatase Rho is implicated in myosin light chain (MLC) phosphorylation, which results in contraction of smooth muscle and interaction of actin and myosin in nonmuscle cells. The guanosine triphosphate (GTP)-bound, active form of RhoA (GTP.RhoA) specifically interacted with the myosin-binding subunit (MBS) of myosin phosphatase, which regulates the extent of phosphorylation of MLC.