中文名稱:BAAT抗原(重組蛋白)
英文名稱: BAAT Antigen (Recombinant Protein)
別 名: BAT; BACAT
儲 存: 冷凍(-20℃)
相關(guān)類別: 抗原
概 述:
Fusion protein corresponding to C terminal 250 amino acids of human BAAT |
Full name: |
bile acid CoA: amino acid N-acyltransferase (glycine N-choloyltransferase) |
Synonyms: |
BAT; BACAT |
Swissprot: |
Q14032 |
Gene Accession: |
BC009567 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
The protein encoded by this gene is a liver enzyme that catalyzes the transfer of C24 bile acids from the acyl-CoA thioester to either glycine or taurine, the second step in the formation of bile acid-amino acid conjugates. The bile acid conjugates then act as a detergent in the gastrointestinal tract, which enhances lipid and fat-soluble vitamin absorption. Defects in this gene are a cause of familial hypercholanemia (FHCA). Two transcript variants encoding the same protein have been found for this gene. |