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  • MAP2K5抗原（重組蛋白）

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    • 品牌 : 通蔚生物
    • 目錄號 : TW16795
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫存：40
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中文名稱： MAP2K5抗原（重組蛋白）

英文名稱： MAP2K5 Antigen (Recombinant Protein)

別      名： MEK5, MAPKK5, PRKMK5, HsT17454

儲      存： 冷凍（-20℃）

相關(guān)類別： 抗原

概述

Fusion protein corresponding to a region derived from 172-409 amino acids of human MAP2K5

技術(shù)規(guī)格

Full name:

mitogen-activated protein kinase kinase 5

Synonyms:

MEK5, MAPKK5, PRKMK5, HsT17454

Swissprot:

Q13163

Gene Accession:

BC008838

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically interacts with and activates MAPK7/ERK5. This kinase itself can be phosphorylated and activated by MAP3K3/MEKK3, as well as by atypical protein kinase C isoforms (aPKCs). The signal cascade mediated by this kinase is involved in growth factor stimulated cell proliferation and muscle cell differentiation. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been described.