中文名稱:CAPNS1抗原(重組蛋白)
英文名稱:CAPNS1 Antigen (Recombinant Protein)
儲 存:冷凍(-20℃)
相關(guān)類別:抗原
概述
Fusion protein corresponding to a region derived from 91-268 amino acids of human CAPNS1 |
技術(shù)規(guī)格
Full name: |
calpain, small subunit 1 |
Synonyms: |
30K, CANP, CDPS, CSS1, CANPS, CAPN4, CALPAIN4 |
Swissprot: |
P04632 |
Gene Accession: |
BC000592 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
Calpains are a ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. Calpain families have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. Calpain I and II are heterodimeric with distinct large subunits associated with common small subunits, all of which are encoded by different genes. This gene encodes a small subunit common to both calpain I and II and is associated with myotonic dystrophy. Two transcript variants encoding the same protein have been identified for this gene. |