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021-54845833/15800441009
英文名稱： Anti-HUWE1 rabbit polyclonal antibody
反應(yīng)種屬： Human, Mouse, Rat
標(biāo) 記 物： Unconjugate
克隆類型： rabbit polyclonal
Background:
This gene encodes a protein containing a C-terminal HECT (E6AP type E3 ubiquitin protein ligase) domain that functions as an E3 ubiquitin ligase. The encoded protein is required for the ubiquitination and subsequent degradation of the anti-apoptotic protein Mcl1 (myeloid cell leukemia sequence 1 (BCL2-related)). This protein also ubiquitinates the p53 tumor suppressor, core histones, and DNA polymerase beta. Mutations in this gene are associated with Turner type X-linked syndromic mental retardation.
Applications:
ELISA, IHC
Name of antibody:
HUWE1
Immunogen:
Synthetic peptide of human HUWE1
Full name:
HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
Synonyms:
MULE; Ib772; LASU1; UREB1; HECTH9; URE-B1; ARF-BP1; HSPC272
SwissProt:
Q7Z6Z7
ELISA Recommended dilution:
5000-10000
IHC positive control:
Human esophagus cancer and human lung cancer
IHC Recommend dilution:
10-50
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