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    • 品牌 : 通蔚生物
    • 目錄號 : TW7606
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
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中文名稱: 兔抗HDAC5 (Phospho-Ser498)多克隆抗體

英文名稱: Anti-HDAC5 (Phospho-Ser498) rabbit polyclonal antibody

別      名: HD5; NY-CO-9

相關(guān)類別: 一抗

儲      存: 冷凍(-20℃) 避光

宿      主: Rabbit

抗      原: HDAC5 (Phospho-Ser498)
反應(yīng)種屬: Human, Mouse, Rat

標(biāo) 記 物: Unconjugate

克隆類型: rabbit polyclonal

技術(shù)規(guī)格

Background:

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by HDAC5 belongs to the class II histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with HDAC3 family member and might form multicomplex proteins. It also interacts with myocyte enhancer factor-2 (MEF2) proteins, resulting in repression of MEF2-dependent genes. This gene is thought to be associated with colon cancer. Two transcript variants encoding different isoforms have been found for this gene.

Applications:

WB, IHC

Name of antibody:

HDAC5 (Phospho-Ser498)

Immunogen:

Synthetic peptide of human HDAC5 (Phospho-Ser498)

Full name:

histone deacetylase 5 (Phospho-Ser498)

Synonyms:

HD5; NY-CO-9

SwissProt:

Q9UQL6

IHC positive control:

Human breast carcinoma

IHC Recommend dilution:

50-100

WB Predicted band size:

122 kDa

WB Positive control:

293 cells untreated or treated with serum starvation

WB Recommended dilution:

500-1000