購(gòu)物車
幫助
021-54845833/15800441009
中文名稱：小鼠抗GRK2單克隆抗體
技術(shù)規(guī)格
Background:
The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart.
Applications:
WB
Name of antibody:
GRK2
Immunogen:
Fusion protein of human GRK2
Full name:
G protein-coupled receptor kinase 2
Synonyms:
BARK1; ADRBK1; BETA-ARK1
SwissProt:
P25098
WB Predicted band size:
80 kDa
WB Positive control:
THP-1 and Ramos cell lysates
WB Recommended dilution:
200-1000
