中文名稱: ZUP1 抗原(重組蛋白)
英文名稱: ZUP1 Antigen (Recombinant Protein)
別 名: zinc finger containing ubiquitin peptidase 1; DUB; ZUFSP; C6orf113
相關(guān)類別: 抗原
儲 存: 冷凍(-20℃)
概 述
Full name: |
zinc finger containing ubiquitin peptidase 1 |
Synonyms: |
DUB; ZUFSP; C6orf113 |
Swissprot: |
Q96AP4 |
Gene Accession: |
BC016879 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
This gene encodes a protein containing zinc finger motifs and a cysteine peptidase domain. The encoded protein functions as a K63-specific de-ubiquitinating enzyme that specifically cleaves long K63-linked polyubiquitin chains in the middle of a chain (i.e. "endo cleavage) rather than by removing the terminal ubiquitin from a chain. This enzyme is thought to be involved in the regulation of DNA repair by cleaving K63-linked ubiquitin chains at repair foci. This protein is related to proteases for the ubiquitin-like modifiers Ufm1 (ubiquitin fold modifier 1) and Atg8/Gabarapl2, but does not have any activity on these modifiers. [provided by RefSeq, Mar 2018] |