中文名稱: WDFY3 抗原(重組蛋白)
英文名稱: WDFY3 Antigen (Recombinant Protein)
別 名: WD repeat and FYVE domain containing 3; ALFY; ZFYVE25
相關(guān)類別:抗原
儲(chǔ) 存: 冷凍(-20℃)
概 述
Fusion protein corresponding to a region derived from 3327-3526 amino acids of human WDFY3
技術(shù)規(guī)格
Full name: |
WD repeat and FYVE domain containing 3 |
Synonyms: |
ALFY; ZFYVE25 |
Swissprot: |
Q8IZQ1 |
Gene Accession: |
BC015214 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
This gene encodes a phosphatidylinositol 3-phosphate-binding protein that functions as a master conductor for aggregate clearance by autophagy. This protein shuttles from the nuclear membrane to colocalize with aggregated proteins, where it complexes with other autophagic components to achieve macroautophagy-mediated clearance of these aggregated proteins. However, it is not necessary for starvation-induced macroautophagy. |