中文名稱: USP14 抗原(重組蛋白)
英文名稱: USP14 Antigen (Recombinant Protein)
別 名: ubiquitin specific peptidase 14; TGT
相關(guān)類別:抗原
儲(chǔ) 存: 冷凍(-20℃)
概 述
Full name: |
ubiquitin specific peptidase 14 |
Synonyms: |
TGT |
Swissprot: |
P54578 |
Gene Accession: |
BC003556 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
This gene encodes a member of the ubiquitin-specific processing (UBP) family of proteases that is a deubiquitinating enzyme (DUB) with His and Cys domains. This protein is located in the cytoplasm and cleaves the ubiquitin moiety from ubiquitin-fused precursors and ubiquitinylated proteins. Mice with a mutation that results in reduced expression of the ortholog of this protein are retarded for growth, develop severe tremors by 2 to 3 weeks of age followed by hindlimb paralysis and death by 6 to 10 weeks of age. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. |