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  • TRPC4AP 抗原（重組蛋白）

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    • 品牌 : 通蔚生物
    • 目錄號 : TW5808
    • 應用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫存：20
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中文名稱： TRPC4AP 抗原（重組蛋白）

英文名稱： TRPC4AP Antigen (Recombinant Protein)

別     名： transient receptor potential cation channel, subfamily C, member 4 associated protein; TRUSS; TRRP4AP; PPP1R158; C20orf188

儲     存： 冷凍（-20℃）

相關類別：抗原

概     述

Fusion protein corresponding to C terminal 200 amino acids of human TRPC4AP

技術規(guī)格

Full name:

transient receptor potential cation channel, subfamily C, member 4 associated protein

Synonyms:

TRUSS; TRRP4AP; PPP1R158; C20orf188

Swissprot:

Q8TEL6

Gene Accession:

BC013144

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

TRPC4AP (transient receptor potential cation channel, subfamily C, member 4 associated protein), also known as TRUSS or TRRP4AP, is a 797 amino acid protein that is expressed in a variety of tissues, with highest expression in liver, heart, testis and brain. Thought to function as a scaffolding protein, TRPC4AP interacts with TNF-R1 and may both link TNF-R1 to the IKK signalsome complex, and participate in the activation of NFκB p50, an event that occurs in response to TNF-R1 ligation. TRPC4AP exists as multiple alternatively spliced isoforms that are encoded by a gene which maps to human chromosome 20. Comprising approximately 2% of the human genome, chromosome 20 contains nearly 63 million bases that encode over 600 genes, some of which are associated with Creutzfeldt-Jakob disease, amyotrophic lateral sclerosis, spinal muscular atrophy, ring chromosome 20 epilepsy syndrome and Alagille syndrome.