中文名稱:TCAP 抗原(重組蛋白)
英文名稱:TCAP Antigen (Recombinant Protein)
別 名: titin-cap; TELE; CMD1N; CMH25; T-cap; LGMD2G; LGMDR7; telethonin
儲 存: 冷凍(-20℃)
相關(guān)類別:抗原
概 述
技術(shù)規(guī)格
Full name: |
titin-cap |
Synonyms: |
TELE; CMD1N; CMH25; T-cap; LGMD2G; LGMDR7; telethonin |
Swissprot: |
O15273 |
Gene Accession: |
BC013330 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
Sarcomere assembly is regulated by the muscle protein titin. Titin is a giant elastic protein with kinase activity that extends half the length of a sarcomere. It serves as a scaffold to which myofibrils and other muscle related proteins are attached. This gene encodes a protein found in striated and cardiac muscle that binds to the titin Z1-Z2 domains and is a substrate of titin kinase, interactions thought to be critical to sarcomere assembly. Mutations in this gene are associated with limb-girdle muscular dystrophy type 2G. |