中文名稱: SENP5 抗原(重組蛋白)
英文名稱: SENP5 Antigen (Recombinant Protein)
別 名: SUMO specific peptidase 5
儲(chǔ) 存: 冷凍(-20℃)
相關(guān)類別:抗原
概 述
技術(shù)規(guī)格
Full name: |
SUMO specific peptidase 5 |
Swissprot: |
Q96HI0 |
Gene Accession: |
BC030705 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
The reversible posttranslational modification of proteins by the addition of small ubiquitin-like SUMO proteins (see SUMO1; MIM 601912) is required for numerous biologic processes. SUMO-specific proteases, such as SENP5, are responsible for the initial processing of SUMO precursors to generate a C-terminal diglycine motif required for the conjugation reaction. They also have isopeptidase activity for the removal of SUMO from high molecular mass SUMO conjugates (Di Bacco et al., 2006 [PubMed 16738315]). |