中文名稱: RGS6 抗原(重組蛋白)
英文名稱: RGS6 Antigen (Recombinant Protein)
別 名: regulator of G protein signaling 6; GAP; S914; HA117
相關類別:抗原
概 述
技術規(guī)格
Full name: |
regulator of G protein signaling 6 |
Synonyms: |
GAP; S914; HA117 |
Swissprot: |
P49758 |
Gene Accession: |
BC113572 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
This gene encodes a member of the RGS (regulator of G protein signaling) family of proteins, which are defined by the presence of a RGS domain that confers the GTPase-activating activity of these proteins toward certain G alpha subunits. This protein also belongs to a subfamily of RGS proteins characterized by the presence of DEP and GGL domains, the latter a G beta 5-interacting domain. The RGS proteins negatively regulate G protein signaling, and may modulate neuronal, cardiovascular, lymphocytic activities, and cancer risk. Many alternatively spliced transcript variants encoding different isoforms with long or short N-terminal domains, complete or incomplete GGL domains, and distinct C-terminal domains, have been described for this gene, however, the full-length nature of some of these variants is not known. |