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  • CDH16 抗原(重組蛋白)

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    • 品牌 : 通蔚生物
    • 目錄號(hào) : TW4215
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫(kù)存:20
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中文名稱: CDH16 抗原(重組蛋白)

英文名稱:CDH16 Antigen (Recombinant Protein)

別    名: cadherin 16

儲(chǔ)    存: 冷凍(-20℃)

相關(guān)類別:抗原

概    述

Fusion protein corresponding to a region derived from 630-829 amino acids of human CDH16

技術(shù)規(guī)格

Full name:

cadherin 16

Swissprot:

O75309

Gene Accession:

BC027912

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. Mapped to a previously identified cluster of cadherin genes on chromosome 16q22.1, the gene localizes with superfamily members CDH1, CDH3, CDH5, CDH8 and CDH11. The protein consists of an extracellular domain containing 6 cadherin domains, a transmembrane region and a truncated cytoplasmic domain but lacks the prosequence and tripeptide HAV adhesion recognition sequence typical of most classical cadherins. Expression is exclusively in kidney, where the protein functions as the principal mediator of homotypic cellular recognition, playing a role in the morphogenic direction of tissue development. Alternatively spliced transcript variants encoding distinct isoforms have been identified.