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  • CASR 抗原(重組蛋白)

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    • 品牌 : 通蔚生物
    • 目錄號 : TW4064
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫存:20
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中文名稱: CASR 抗原(重組蛋白)

英文名稱:CASR Antigen (Recombinant Protein)

別      名:calcium sensing receptor; CAR; FHH; FIH; HHC; EIG8; HHC1; NSHPT; PCAR1; GPRC2A; HYPOC1

儲      存:冷凍(-20℃)

相關(guān)類別:抗原

概     述

Fusion protein corresponding to a region derived from 908-1078 amino acids of human CASR

技術(shù)規(guī)格

Full name:

calcium sensing receptor

Synonyms:

CAR; FHH; FIH; HHC; EIG8; HHC1; NSHPT; PCAR1; GPRC2A; HYPOC1

Swissprot:

P41180

Gene Accession:

BC112236

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The protein encoded by this gene is a G protein-coupled receptor that is expressed in the parathyroid hormone (PTH)-producing chief cells of the parathyroid gland, and the cells lining the kidney tubule. It senses small changes in circulating calcium concentration and couples this information to intracellular signaling pathways that modify PTH secretion or renal cation handling, thus this protein plays an essential role in maintaining mineral ion homeostasis. Mutations in this gene cause familial hypocalciuric hypercalcemia, familial, isolated hypoparathyroidism, and neonatal severe primary hyperparathyroidism.